Endocrine Abstracts

Introduction: An undefined lesion detected by imaging methods in one or both adrenals is known as an incidentaloma. The size and capacity of the secretion are evaluated to determine its definitive management. It is extremely uncommon for a mixed adrenal incidentaloma to appear with elevated cortisol and medullar hormone output.Case report: A 21-year-old woman was admitted to the hospital with intermittent palpitations, headaches, and chest pain. She was ...

Thyrotoxic periodic paralysis (TPP) is uncommon complication of Graves’ disease mainly observed in young males of Asian origin. It is rarely seen among white hyperthyroid patients (0.1–0.2%), usually presented as lower extremities muscle weakness of sudden onset, probably cause by hypokalemia. Possible mechanism of hypokalemia is an increased sodium–potassium–adenosine triphosphatase pump activity with consequent massive shift og potassium from extracellula...

Background: We know that lipid profile is disturbed in both subclinical hypothyroidism (SH) and metabolic syndrome (MetSy). In this study we observed lipid profile in newly diagnosed patients with SH and MetSy.Materials and methods: We chose 70 patients (all females) with newly discovered SH and 20 healthy controls, mean age 51.1 (±6.79). The parameters that we determined are: TSH, FT4, anti-TPO-At, triglycerides, whole, LDL and HDL chole...

Introduction: Ectopic thyroid tissue is a rare developmental abnormality with the prevalence of 1 per 100.000–300.000 persons in the general population. It is most commonly detected in younger women and presented as lingual thyroid. Here we report a rare case of ectopic thyroid tissue in the left adrenal gland.Case report: A 29-year old female without previous medical history was incidentally diagnosed with left adrenal gland mass detected on routi...

Background: Recently many authors are questioning the existing of elements of metabolic syndrome (MetSy) in patients with subclinical hypothyroidism (SH). In this cross sectional study we observed glycemia, as an element of MetSy, in newly diagnosed patients with SH.Materials and methods: Seventy females participated in study. Among them there were 50 patients with SH, mean age 58.3 (±8.53), and 20 controls without SH, mean age 51.1 (±6.79). We...

Introduction: By using insulin analogue, it is expected to improve glycemic regulation in poorly controlled type 2 diabetes (t2DM). The aim of the study was to examine the quality of glycemic control and quality of life (QoL) of patients managed with insulin analogues, previously treated with human insulin.Materials and methods: The pilot study included 30 t2DM outpatients, divided into two groups (15 subjects) – the first group was treated with hum...

Background and aim: Iron overload and inflammation might participate in the pathogenesis of insulin resistance in community. The improvement of insulin resistance in hemodialysis (HD) patients is frequently seen after correction of anemia. The aim of this study was to investigate the influence of recobinant humam erythropoietin (Epo) treatment on insulin resistance in non-diabetic HD patients.Patients and methods: We investigated the effects of 6 months-...

Introduction: Subclinical and clinical primary hypothyroidism potentially makes a negative influence on the patient’s quality of life. Present study examined the level of hypothyroid symptoms and signs expression as well patient’s quality of life before levothyroxine and after substitutionally-induced laboratory euthyroidism.Material and methods: Prospective case–control study consisted of 75 female patients divided into three groups based...

Propylthiouracil (PTU) sometimes induces autoimmune syndromes, such as PTU–induced lupus or vasculitis. Here we present hands and feet vasculitis-like skin changes observed several days after PTU introduction in a patient who suffered from serious diffuse toxic goiter. Because of segmental distribution, normal liver function test, and no signs of clinical deterioration, it was decided to continue PTU management and observe the patient. Primarily maculopapular rash became ...

Introduction: A number of studies reported that almost every fifth patient with thalassemia hav e diabetes. Various factors could contribute to inadequate retrograde glycemic control in thalassemia patients co-existed with diabetes. According to published data, HbA1C seems to be an insufficient marker of the quality of diabetes control in thalassemia patients.Case report: We present a male 67 years old type 2 diabetes patient with disease history for 15 ...